Featured Publications

Dynamic Light’s SpeckleView® technology has 20 years of research evidence to support its utility in the operating room. Back in 2001, co-founder Dr. Andrew Dunn demonstrated the first use of laser speckle to image blood flow in a rodent brain. Dr. Dunn translated the use of laser speckle to the operating room and published a seminal paper in 2010 demonstrating the ability of SpeckleView technology to monitor cerebral blood flow during neurosurgery. This was followed with a demonstration of SpeckleView technology with an endoscope in 2013. A 2014 paper showed the utility of SpeckleView technology in 10 neurosurgery patients, followed by a 2017 demonstration of quantitative blood flow monitoring in 8 neurosurgery cases. A 2022 manuscript by Dr. Dunn and co-founder Dr. David Miller directly compared SpeckleView with indocyanine green angiography demonstrating that the techniques provide different, yet complementary information about vessel perfusion. A recent 2023 paper by Dr. Dunn and Dr. Miller demonstrated the utility of SpeckleView for cerebrovascular and brain tumor cases with renowned neurosurgeon Dr. Andreas Raabe, who pioneered the use of Indocyanine green angiography in neurosurgery.

Comparison of Indocyanine Green Angiography and Laser Speckle Contrast Imaging for the Assessment of Vasculature Perfusion
Laser speckle contrast imaging of blood flow in rat retinas using an endoscope
Laser speckle contrast imaging of cerebral blood flow in humans during neurosurgery: a pilot clinical study
Intraoperative multi-exposure speckle imaging of cerebral blood flow
Intraoperative laser speckle contrast imaging with retrospective motion correction for quantitative assessment of cerebral blood flow
Continuous blood flow visualization with laser speckle contrast imaging during neurovascular surgery
Laser speckle contrast imaging for visualizing blood flow during cerebral aneurysm surgery: A comparison with indocyanine green angiography
Intraoperative Laser Speckle Contrast Imaging to Assess Vessel Flow in Neurosurgery: A Pilot Study
Sedation with dexmedetomidine decreases skin perfusion in cats
Intraoperative Laser Speckle Contrast Imaging to Assess Vessel Flow in Neurosurgery: A Pilot Study
Dynamic Imaging of Cerebral Blood Flow Using Laser Speckle
Laser speckle contrast imaging versus microvascular Doppler sonography in aneurysm surgery: A prospective study
Cortical perfusion measurements with laser speckle contrast imaging during adenosine induced cardiac arrest for aneurysm clipping: a case report
Continuous hemodynamics monitoring during arteriovenous malformation microsurgical resection with laser speckle contrast imaging: case report